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This makes them water-soluble and able to be excreted through urine or feces.[ref] Essentially, these two steps need to work in tandem: Phase I : The CYP1B1 or CYP1A1 enzyme breaks down estradiol into the catechol estrogen metabolites

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P.PaolicelliD.ZipoliV.et al (2016)

This is why many clients notice a difference in energy and clarity within 48 to 72 hours of their first injection

For anyone considering GHK-Cu, my advice is simple: give it time, stay consistent, and keep your expectations realistic

So, if you're someone who is unsure or has medical conditions, its suggested that you speak with a healthcare professional before starting any supplement.vb